Hallmark Peptides Catalog
SKU MTC10-0428 · Longevity & Cellular Health
MOTS-c
MOTS-c is a mitochondria-derived peptide (MDP) of 16 amino acids, encoded by the mitochondrial 12S rRNA gene, functioning as a metabolic regulator and systemic "mitokine".
Product code
MTC10-0428
Availability
In Stock · 100 units
Purchase highlights
Mitochondria-derived peptide encoded by the 12S rRNA gene
AMPK activation and systemic metabolic regulation ("mitokine")
Lyophilized · ≥98% purity · CAS 1627580-64-6
Description
HTML contentMOTS-c is a novel mitochondria-derived peptide (MDP) composed of 16 amino acids, encoded by the mitochondrial genome within the 12S rRNA gene. Discovered in 2015, MOTS-c is one of only two known mitochondrial-derived peptides and functions as both a cell-specific regulatory signal and a systemic hormone — earning it the designation "mitokine."
MOTS-c primarily targets skeletal muscle and acts as a metabolic regulator by activating the AMPK pathway, the master switch for cellular energy homeostasis. Under metabolic stress, MOTS-c translocates to the cell nucleus where it interacts with stress-responsive transcription factors including NRF2.
Additional information
Category
Longevity & Cellular Health
CAS Number
1627580-64-6
Availability
In stock
Delivery
10–14 business days
Coverage
United States, European Union, South America
Regulatory notice
Regulatory Compliance Notice
- Exclusively for laboratory research use
- Not intended for human or veterinary use
- Not intended for human consumption
- Not intended to diagnose, treat, cure, or prevent any disease
- Not approved by the FDA as a drug or dietary supplement
Technical Specifications
Product dataCAS Number
1627580-64-6
Package Size
10 mg
Expiry
April 2028
PubChem
PubChem CID 146675088
Storage
-20 °C (lyophilized); 2–8 °C after reconstitution
Purity
≥ 98% (HPLC)
Format
Lyophilized powder
Manufacturer
Hallmark Peptides
Warnings
Product dataResearch use only
For laboratory research use only. Not intended for human or veterinary use.
Handling
Handle with appropriate laboratory safety equipment.
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